Carlo Fisicaro and Fabio Airoldi Present Peptone’s Ultra-Scalable Architecture at KubeCon 2025

Carlo Fisicaro and Fabio Airoldi on stage for KubeCon 2025

KubeCon, the Cloud Native Computing Foundation’s flagship conference, is a premier event that brings together adopters and technologists from the leading open-source and cloud-native communities. This conference is a hub for innovation and collaboration, focusing on Kubernetes and other cloud-native technologies. It provides a platform for industry leaders to share their insights, advancements, and real-world applications of these technologies. The significance of KubeCon lies in its ability to showcase cutting-edge developments and foster discussions that shape the future of cloud-native computing.

KubeCon + CloudNativeCon is a major conference focused on cloud-native computing and Kubernetes, organized by the Cloud Native Computing Foundation (CNCF). It serves as a gathering for developers, engineers, and industry leaders to discuss the latest advancements, best practices, and future directions in cloud-native technologies and Kubernetes.

At the recent KubeCon + CloudNativeCon Europe 2025 in London, Carlo Fisicaro, the Chief Technology Officer of Peptone, and Fabio Airoldi took the stage to present to an audience of over 8,000 attendees. Their presentation focused on Peptone’s ultra-scalable computing and data processing architecture, which is powered by Kubernetes and Amazon Web Services (AWS). This architecture is designed to handle the complex computational demands of protein structure prediction, leveraging both model and data parallelism to efficiently sample conformational spaces. By utilizing Kubernetes to orchestrate workloads across GPU nodes, Peptone’s system demonstrates a practical application of cloud-native technologies in the biotech industry, highlighting how these tools can be used to create scalable solutions for computationally intensive tasks.

KubeCon + CloudNativeCon is important because it's the flagship conference for the Cloud Native Computing Foundation (CNCF), bringing together adopters and technologists from leading open source and cloud native communities. It serves as a key platform for education, collaboration, and the advancement of cloud native computing, with a strong focus on Kubernetes. The event is crucial for staying updated on the latest trends, sharing insights, and networking with key players in the Kubernetes and broader cloud native ecosystem.

Their presentation was part of a broader lineup that included industry giants such as Spotify and Apple. Spotify and Apple, both known for their innovative use of cloud-native technologies, presented their own approaches to managing large-scale platforms and services. Spotify’s presentation likely focused on their use of Kubernetes to handle their vast music streaming infrastructure, while Apple’s discussion may have centered on their Private Cloud Compute (PCC) system, which supports Apple Intelligence features while prioritizing user privacy. The inclusion of these companies underscores the significance of KubeCon as a platform for sharing advancements in cloud-native computing across diverse sectors.

At KubeCon + CloudNativeCon Europe 2025 in London, Tyson Singer, Spotify's head of technology and platforms, presented during the keynote, discussing Backstage's journey.

In conclusion, Carlo Fisicaro and Fabio Airoldi’s presentation at KubeCon was a testament to Peptone’s innovative approach to leveraging cloud-native technologies for biotech applications. Their ultra-scalable architecture, powered by Kubernetes and AWS, exemplifies the potential of these technologies to transform industries beyond traditional tech sectors. The presence of other industry leaders like Spotify and Apple further solidified KubeCon’s status as a pivotal event for the cloud-native community.